American Journal of Cardiology
Volume 93, Issue 1 , Pages 10-13 , 1 January 2004

Usefulness of attenuated heart rate recovery immediately after exercise to predict endothelial dysfunction in patients with suspected coronary artery disease

  • Po-Hsun Huang, MD

      Affiliations

    • Division of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    • Institute of Clinical Medicine, Taipei, Taiwan
    • Cardiovascular Research Center, National Yang-Ming University, Taipei, Taiwan
    • ,
  • Hsin-Bang Leu, MD

      Affiliations

    • Division of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    • Institute of Clinical Medicine, Taipei, Taiwan
    • Cardiovascular Research Center, National Yang-Ming University, Taipei, Taiwan
    • ,
  • Jaw-Wen Chen, MD

      Affiliations

    • Division of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    • Institute of Clinical Medicine, Taipei, Taiwan
    • Cardiovascular Research Center, National Yang-Ming University, Taipei, Taiwan
    • ,
  • Chien-Ming Cheng, MD

      Affiliations

    • Division of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    • Institute of Clinical Medicine, Taipei, Taiwan
    • Cardiovascular Research Center, National Yang-Ming University, Taipei, Taiwan
    • ,
  • Chun-Yao Huang, MD

      Affiliations

    • Division of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    • Institute of Clinical Medicine, Taipei, Taiwan
    • Cardiovascular Research Center, National Yang-Ming University, Taipei, Taiwan
    • ,
  • Ta-Chuan Tuan, MD

      Affiliations

    • Division of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    • Institute of Clinical Medicine, Taipei, Taiwan
    • Cardiovascular Research Center, National Yang-Ming University, Taipei, Taiwan
    • ,
  • Philip Yu-An Ding, MD, PhD

      Affiliations

    • Division of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    • Institute of Clinical Medicine, Taipei, Taiwan
    • Cardiovascular Research Center, National Yang-Ming University, Taipei, Taiwan
    • ,
  • Shing-Jong Lin, MD, PhD

      Affiliations

    • Division of Cardiology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
    • Institute of Clinical Medicine, Taipei, Taiwan
    • Cardiovascular Research Center, National Yang-Ming University, Taipei, Taiwan
    • Corresponding Author InformationAddress for reprints: Shing-Jong Lin, MD, PhD, Division of Cardiology, Taipei Veterans General Hospital, No. 201, Sec. 2, Shih-Pai Road, Taipei, Taiwan.

Received 8 July 2003 ,Revised 9 September 2003 ,Accepted 9 September 2003.

References 

  1. Corretti MC, Anderson TJ, Benjamin EJ, Celemajer DS, Charbonneau F, Creager MA, et al  Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery. J Am Coll Cardiol. 2002;39:257–265
  2. Cole CR, Blackstone EH, Pashkow FJ, Sander CE, Lauer MS. Heart-rate recovery immediately after exercise as a predictor of mortality. N Engl J Med. 1999;341:1351–1357
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  12. Hijmering ML, Stroes ES, Olijhoek J, Hutten BA, Blankestijn PJ, Rabelink TJ. Sympathetic activation markedly reduces endothelium-dependent, flow-mediated vasodilation. J Am Coll Cardiol. 2002;39:683–688
  13. Ghiadoni L, Donald AE, Cropley M, Mullen MJ, Oakley G, Taylor M, et al. Mental stress induces transient endothelial dysfunction in humans. Circulation. 2000;102:2473–2478
  14. Cohn JN, Levine TB, Olivari MT, Garberg V, Lura D, Francies GS, et al. Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failure. N Engl J Med. 1984;311:819–823

☆ This study was partly supported by research grants NSC 91-2314-B-010-059 from the National Science Councils, Taipei; VGH 91-256 and VTY 91-P1-03 from Taipei Veterans General Hospital, Teipei; and CI-91-6-1 from the Yen Tjing-Ling Medical Foundation, Taipei, Taiwan.

PII: S0002-9149(03)01320-1

doi: 10.1016/j.amjcard.2003.09.004

American Journal of Cardiology
Volume 93, Issue 1 , Pages 10-13 , 1 January 2004

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