American Journal of Cardiology
Volume 109, Issue 4 , Pages 533-537, 15 February 2012

White Blood Cell Count and Risk of Incident Atrial Fibrillation (From the Framingham Heart Study)

  • Michiel Rienstra, MD, PhD

      Affiliations

    • Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts
    • Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    • Framingham Heart Study, National Heart, Lung, and Blood Institute and Boston University, Framingham, Massachusetts
    • ,
  • Jenny X. Sun, PhD

      Affiliations

    • Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts
    • ,
  • Jared W. Magnani, MD

      Affiliations

    • Framingham Heart Study, National Heart, Lung, and Blood Institute and Boston University, Framingham, Massachusetts
    • Cardiology Section, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts
    • ,
  • Moritz F. Sinner, MD

      Affiliations

    • Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts
    • Framingham Heart Study, National Heart, Lung, and Blood Institute and Boston University, Framingham, Massachusetts
    • Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians University, Munich, Germany
    • ,
  • Steven A. Lubitz, MD, MPH

      Affiliations

    • Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, Massachusetts
    • ,
  • Lisa M. Sullivan, PhD

      Affiliations

    • Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts
    • ,
  • Patrick T. Ellinor, MD, PhD

      Affiliations

    • Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts
    • Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, Massachusetts
    • Drs. Ellinor and Benjamin contributed equally to this article.
    • ,
  • Emelia J. Benjamin, MD, ScM

      Affiliations

    • Framingham Heart Study, National Heart, Lung, and Blood Institute and Boston University, Framingham, Massachusetts
    • Cardiology Section, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts
    • Preventive Medicine Section, Boston University School of Medicine, Boston, Massachusetts
    • Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts
    • Corresponding Author InformationCorresponding author: Tel: (617) 638-8968; fax: (508) 626-1262
    • Drs. Ellinor and Benjamin contributed equally to this article.

Received 22 June 2011; received in revised form 29 September 2011; accepted 29 September 2011. published online 21 November 2011.

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 The Framingham Heart Study is supported by grant N01-HC-25195 from the National Heart, Lung, and Blood Institute, Bethesda, Maryland and by Boston University School of Medicine, Boston, Massachusetts. Dr. Rienstra is supported by Rubicon grant 825.09.020 from The Netherlands Organization for Scientific Research, The Hague, The Netherlands; Dr. Magnani is supported by American Heart Association Award 09FTF2190028 (Dallas, Texas). Dr. Sinner is supported by the German Heart Foundation (Frankfurt, Germany). This work was supported by grant 1R01HL092577 from the National Institutes of Health, Bethesda, Maryland to Drs. Benjamin and Ellinor, grants 1RC1HL101056, 1R01HL102214, and R01AG028321 and support via grant 6R01-NS 17950 to Dr. Benjamin, and grants 5R21DA027021, 5RO1HL104156, 1K24HL105780 to Dr. Ellinor. This study was partially supported by the Evans Center for Interdisciplinary Biomedical Research ARC on Atrial Fibrillation Initiative (Boston University, Boston, Massachusetts).

PII: S0002-9149(11)03044-X

doi:10.1016/j.amjcard.2011.09.049

American Journal of Cardiology
Volume 109, Issue 4 , Pages 533-537, 15 February 2012

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