American Journal of Cardiology
Volume 104, Issue 6 , Pages 823-828 , 15 September 2009

Effect of Habitual Aerobic Exercise on Body Weight and Arterial Function in Overweight and Obese Men

Received 22 February 2009 ,Revised 27 April 2009 ,Accepted 27 April 2009.

References 

  1. Silventoinen K, Sans S, Tolonen H, Monterde D, Kuulasmaa K, Kesteloot H, et al. Trends in obesity and energy supply in the WHO MONICA project. Int J Obes. 2004;28:710–718
  2. Nishitani N, Sakakibara H, Akiyama I. Eating behavior related to obesity and job stress in male Japanese workers. Nutrition. 2009;25:45–50
  3. Yan LL, Daviglus ML, Liu K, Stamler J, Wang R, Pirzada A, et al. Midlife body mass index and hospitalization and mortality in older age. JAMA. 2006;295:190–198
  4. Cui R, Toyoshima H, Date C, Yamamoto A, Kikuchi S, Kondo T, et al. Body mass index and mortality from cardiovascular disease among Japanese men and women: the JACC study. Stroke. 2005;36:1377–1382
  5. Tanaka H, Dinenno FA, Monahan KD, Clevenger CM, DeSouza CA, Seals DR. Aging, habitual exercise, and dynamic arterial compliance. Circulation. 2000;102:1270–1275
  6. Maeda S, Tanabe T, Otsuki T, Sugawara J, Iemitsu M, Miyauchi T, et al. Moderate regular exercise increases basal production of nitric oxide in elderly women. Hypertens Res. 2004;27:947–953
  7. Maeda S, Tanabe T, Miyauchi T, Otsuki T, Sugawara J, Iemitsu M, et al. Aerobic exercise training reduces plasma endothelin-1 concentration in older women. J Appl Physiol. 2003;95:336–341
  8. Okura T, Nakata Y, Ohkawara K, Numao S, Katayama Y, Ono Y, et al. Effect of weight reduction on concentration of plasma total homocysteine in obese Japanese men. Obese Res. 2007;1:213–221
  9. Van Bortel LM, Duprez D, Starmans-Kool MJ, Safer ME, Giannattasio C, Cockcroft J, et al. Clinical applications of arterial stiffness, task force 3: recommendations for user producers. Am J Hypertens. 2002;15:445–452
  10. Nichols WW, O'Rourke M. Sphygmocardiography. In:  Nichols WW,  O'Rourke M editor. MacDonald's Blood Flow in Arteries: Theoretical, Experimental and Clinical Principles. London-Sydney-Auckland: Arnold E; 1998;p. 453–476
  11. Hirai T, Sasayama S, Kawasaki T, Yagi S. Stiffness of systemic arteries in patients with myocardial infarction: a noninvasive method to predict severity of coronary atherosclerosis. Circulation. 1989;80:78–86
  12. Safar ME, London GMClinical Committee of Arterial StructureFunction. Therapeutic studies and arterial stiffness in hypertension: recommendations of the European Society of Hypertension. J Hypertens. 2000;18:1527–1535
  13. Hodes RJ, Lakatta EG, McNeil CT. Another modifiable risk factor for cardiovascular disease? (Some evidence points to arterial stiffness). J Am Geriatr Soc. 1995;43:581–582
  14. Ingelsson E, Sullivan LM, Fox CS, Murabito JM, Benjamin EJ, Polak JF, et al. Burden and prognostic importance of subclinical cardiovascular disease in overweight and obese individuals. Circulation. 2007;116:375–384
  15. Danias PG, Tritos NA, Stuber M, Botnar RM, Kissinger KV, Manning WJ. Comparison of aortic elasticity determined by cardiovascular magnetic resonance imaging in obese versus lean adults. Am J Cardiol. 2003;91:195–199
  16. Sutton-Tyrrell K, Newman A, Simonsick EM, Havlik R, Pahor M, Lakatta E, et al. Aortic stiffness is associated with visceral adiposity in older adults enrolled in the Study of Health, Aging, and Body Composition. Hypertension. 2001;38:429–433
  17. Wildman RP, Mackey RH, Bostom A, Thompson T, Sutton-Tyrrell K. Measures of obesity are associated with vascular stiffness in young and older adults. Hypertension. 2003;42:468–473
  18. Otsuki T, Maeda S, Iemitsu M, Saito Y, Tanimura Y, Ajisaka R, et al. Vascular endothelium-derived factors and arterial stiffness in strength- and endurance-trained men. Am J Physiol. 2007;292:H786–H791
  19. Kakiyama T, Sugawara J, Murakami H, Maeda S, Kuno S, Matsuda M. Effects of short-term endurance training on aortic distensibility in young men. Med Sci Sports Exerc. 2005;37:267–271
  20. Yamashita T, Sasahara T, Pomeroy SE, Collier G, Nestel PJ. Arterial compliance, blood pressure, plasma leptin, and plasma lipids in women are improved with weight reduction equally with a meat-based diet and plant-based diet. Metabolism. 1998;47:1308–1314
  21. Vaitkevicius PV, Fleg JL, Engel JH, O'Connor FC, Wright JG, Lakatta LE, et al. Effect of age and aerobic capacity on arterial stiffness in healthy adults. Circulation. 1993;88:1456–1462
  22. Meyer AA, Kundt G, Lenschow U, Schuff-Werner P, Kienast W. Improvement of early vascular changes and cardiovascular risk factors in obese children after a six-month exercise program. Am J Coll Cardiol. 2006;48:1865–1870
  23. Sciacqua A, Candigliota M, Cerevolo R, Scozzafava A, Sinopoli F, Corsonello A, et al. Weight loss in combination with physical activity improves endothelial dysfunction in human obesity. Diab Care. 2003;26:1673–1678
  24. Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y, et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature. 1988;332:411–415
  25. Moncada S, Palmer RM, Higgs EA. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev. 1991;43:102–142
  26. Rubanyi GM, Polokoff MA. Endothelin: molecular biology, biochemistry, pharmacology, physiology, and pathophysiology. Pharmacol Rev. 1994;46:325–415
  27. McEniery CM, Qasem A, Schmitt M, Avolio AP, Cockcroft JR, Wilkinson IB. Endothelin-1 regulates arterial pulsewave velocity in vivo. J Am Coll Cardiol. 2003;42:1975–1981
  28. Vuurmans TJ, Boer P, Koomans HA. Effects of endothelin-1 and endothelin-1 receptor blockade on cardiac output, aortic pressure, and pulsewave velocity in humans. Hypertension. 2003;41:1253–1258
  29. Wilkinson IB, Qasem A, McEniery CM, Webb DJ, Avolio AP, Cockcroft JR. Nitric oxide regulates local arterial distensibility in vivo. Circulation. 2002;105:213–217

 This work was supported by Grants-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science, and Technology of Japan, Tokyo, Japan, Grants 18300215 and 21-692.

PII: S0002-9149(09)01055-8

doi: 10.1016/j.amjcard.2009.04.057

American Journal of Cardiology
Volume 104, Issue 6 , Pages 823-828 , 15 September 2009