American Journal of Cardiology
Volume 103, Issue 3 , Pages 295-300 , 1 February 2009

Current Use of Beta Blockers in Patients With Reactive Airway Disease Who Are Hospitalized With Acute Coronary Syndromes

  • Benjamin A. Olenchock, MD, PhD

      Affiliations

    • TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts
    • ,
  • Gregg G. Fonarow, MD

      Affiliations

    • Division of Cardiology, University of California Los Angeles, Los Angeles, California
    • ,
  • Wenqin Pan, PhD

      Affiliations

    • Duke Clinical Research Institute, Durham, North Carolina
    • ,
  • Adrian Hernandez

      Affiliations

    • Duke Clinical Research Institute, Durham, North Carolina
    • ,
  • Christopher P. Cannon, MD

      Affiliations

    • TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts
    • Corresponding Author InformationCorresponding author: Tel: 617-278-0146; fax: 617-734-7329
    • ,
  • Get With The GuidelinesSM Steering Committee

Received 29 July 2008 ,Revised 23 September 2008 ,Accepted 23 September 2008.

References 

  1. Anderson JL, Adams CD, Antman EM, Bridges CR, Califf RM, Casey DE, et al ACC/AHA 2007 guidelines for the management of patients with unstable angina/non ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients With Unstable Angina/Non ST-Elevation Myocardial Infarction): developed in collaboration with the American College of Emergency Physicians, the Society for Cardiovascular Angiography and Interventions, and the Society of Thoracic Surgeons: endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation and the Society for Academic Emergency Medicine. Circulation. 2007;116:e148–e304
  2. Antman EM, Anbe DT, Armstrong PW, Bates ER, Green LA, Hand M, et al ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Revise the 1999 Guidelines for the Management of Patients with Acute Myocardial Infarction). Circulation. 2004;110:e82–e292
  3. Lopez-Sendon J, Swedberg K, McMurray J, Tamargo J, Maggioni AP, Dargie H, et al. Expert consensus document on beta-adrenergic receptor blockers. Eur Heart J. 2004;25:1341–1362
  4. Antman EM, Hand M, Armstrong PW, Bates ER, Green LA, Halasyamani LK, et al 2007 Focused Update of the ACC/AHA 2004 Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines: developed in collaboration with the Canadian Cardiovascular Society endorsed by the American Academy of Family Physicians: 2007 Writing Group to Review New Evidence and Update the ACC/AHA 2004 Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction, Writing on Behalf of the 2004 Writing Committee. Circulation. 2008;117:296–329
  5. Gottlieb SS, McCarter RJ, Vogel RA. Effect of beta-blockade on mortality among high-risk and low-risk patients after myocardial infarction. N Engl J Med. 1998;339:489–497
  6. Kendall MJ, Beeley L. Beta-adrenoceptor blocking drugs: adverse reactions and drug interactions. Pharmacol Ther. 1983;21:351–369
  7. van der Woude HJ, Zaagsma J, Postma DS, Winter TH, van Hulst M, Aalbers R. Detrimental effects of beta-blockers in COPD: a concern for nonselective beta-blockers. Chest. 2005;127:818–824
  8. Hanania NA, Singh S, El-Wali R, Flashner M, Franklin AE, Garner WJ, et al. The safety and effects of the beta-blocker, nadolol, in mild asthma: An open-label pilot study. Pulm Pharmacol Ther. 2008;21:134–141
  9. Callaerts-Vegh Z, Evans KL, Dudekula N, Cuba D, Knoll BJ, Callaerts PF, et al. Effects of acute and chronic administration of beta-adrenoceptor ligands on airway function in a murine model of asthma. Proc Natl Acad Sci U S A. 2004;101:4948–4953
  10. Chen J, Radford MJ, Wang Y, Marciniak TA, Krumholz HM. Effectiveness of beta-blocker therapy after acute myocardial infarction in elderly patients with chronic obstructive pulmonary disease or asthma. J Am Coll Cardiol. 2001;37:1950–1956
  11. Salpeter SR, Ormiston TM, Salpeter EE. Cardioselective beta-blockers in patients with reactive airway disease: a meta-analysis. Ann Intern Med. 2002;137:715–725
  12. Salpeter S, Ormiston T, Salpeter E. Cardioselective beta-blockers for chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2005;CD003566
  13. Lee DK, Borade PS, Currie GP. Safety of beta-blockers in COPD: the jury must still be out. Qjm. 2005;98:706–707
  14. Albouaini K, Andron M, Alahmar A, Egred M. Beta-blockers use in patients with chronic obstructive pulmonary disease and concomitant cardiovascular conditions. Int J Chron Obstruct Pulmon Dis. 2007;2:535–540
  15. Egred M, Shaw S, Mohammad B, Waitt P, Rodrigues E. Under-use of beta-blockers in patients with ischaemic heart disease and concomitant chronic obstructive pulmonary disease. Qjm. 2005;98:493–497
  16. Butler J, Arbogast PG, BeLue R, Daugherty J, Jain MK, Ray WA, et al. Outpatient adherence to beta-blocker therapy after acute myocardial infarction. J Am Coll Cardiol. 2002;40:1589–1595
  17. Smith CS, Cannon CP, McCabe CH, Murphy SA, Bentley J, Braunwald E. Early initiation of lipid-lowering therapy for acute coronary syndromes improves compliance with guideline recommendations: observations from the Orbofiban in Patients with Unstable Coronary Syndromes (OPUS-TIMI 16) trial. Am Heart J. 2005;149:444–450
  18. Fonarow GC. In-hospital initiation of statins: taking advantage of the ‘teachable moment’. Cleve Clin J Med. 2003;70:502;504–506
  19. Fonarow GC. In-hospital initiation of cardiovascular protective medications for patients undergoing percutaneous coronary intervention: taking advantage of the teachable moment. J Invasive Cardiol. 2003;15:646–652

 This study was supported by Get With The GuidelinesSM-CAD, sponsored by the American Heart Association with funding in part from an unrestricted education grant from the Merck-Schering Plough Partnership.

PII: S0002-9149(08)01675-5

doi: 10.1016/j.amjcard.2008.09.081

American Journal of Cardiology
Volume 103, Issue 3 , Pages 295-300 , 1 February 2009

Article Tools

* Image Usage & Resolution