American Journal of Cardiology
Volume 100, Issue 12 , Pages 1759-1766 , 15 December 2007

Exercise Training Amount and Intensity Effects on Metabolic Syndrome (from Studies of a Targeted Risk Reduction Intervention through Defined Exercise)

  • Johanna L. Johnson, MS

      Affiliations

    • Department of Medicine, Division of Cardiology, Duke University Medical Center and Duke Center for Living, Durham, North Carolina
    • Corresponding Author InformationCorresponding author: Tel.: 919-660-6766; Fax: 919-668-3697.
    • ,
  • Cris A. Slentz, PhD

      Affiliations

    • Department of Medicine, Division of Cardiology, Duke University Medical Center and Duke Center for Living, Durham, North Carolina
    • ,
  • Joseph A. Houmard, PhD

      Affiliations

    • Department of Exercise and Sports Science and Human Performance Laboratory, East Carolina University, Greenville, North Carolina
    • ,
  • Gregory P. Samsa, PhD

      Affiliations

    • Department of Medicine, General Internal Medicine, Center for Health Policy Research, Durham, North Carolina
    • Department of Community and Family Medicine, Durham, North Carolina.
    • ,
  • Brian D. Duscha, MS

      Affiliations

    • Department of Medicine, Division of Cardiology, Duke University Medical Center and Duke Center for Living, Durham, North Carolina
    • ,
  • Lori B. Aiken, BS

      Affiliations

    • Department of Medicine, Division of Cardiology, Duke University Medical Center and Duke Center for Living, Durham, North Carolina
    • ,
  • Jennifer S. McCartney, MA

      Affiliations

    • Department of Exercise and Sports Science and Human Performance Laboratory, East Carolina University, Greenville, North Carolina
    • ,
  • Charles J. Tanner, MS

      Affiliations

    • Department of Exercise and Sports Science and Human Performance Laboratory, East Carolina University, Greenville, North Carolina
    • ,
  • William E. Kraus, MD

      Affiliations

    • Department of Medicine, Division of Cardiology, Duke University Medical Center and Duke Center for Living, Durham, North Carolina

Received 2 April 2007 ,Revised 1 July 2007 ,Accepted 1 July 2007.

References 

  1. Panel E. Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA. 2001;285:2486–2497
  2. Kraus W, Torgan C, Duscha B, Norris J, Brown S, Cobb F, et al. Studies of a targeted risk reduction intervention through defined exercise. Med Sci Sports Exerc. 2001;33:1774–1784
  3. Otvos J, Jeyarajah E, Bennett D, Krauss R. Development of a proton nuclear magnetic resonance spectroscopic method for determining plasma lipoprotein concentrations and subspecies distributions from a single, rapid measurement. Clin Chem. 1992;38:1632–1638
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  6. Wijndaele K, Beunen G, Duvigneaud N, Matton L, Duquet W, Thomis M, et al. A continuous metabolic syndrome risk score: utility for epidemiological analyses. Diabetes Care. 2006;29:2329
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  8. Pate R, Pratt M, Blair S, Haskell W, Macera C, Bouchard C, et al. Physical activity and public health (A recommendation from the Centers for Disease Control and Prevention and the American College of Sports Medicine). JAMA. 1995;273:402–407
  9. Blair S, Kohl H, Paffenbarger R, Clark D, Cooper K, Gibbons L. Physical fitness and all-cause mortality (A prospective study of healthy men and women). JAMA. 1989;262:2395–2401
  10. Blair S, Kohl H, Barlow C, Paffenbarger R, Gibbons L, Macera C. Changes in physical fitness and all-cause mortality (A prospective study of healthy and unhealthy men). JAMA. 1995;273:1093–1098
  11. Paffenbarger R, Hyde R, Wing A, Hsieh C. Physical activity, all-cause mortality, and longevity of college alumni. N Engl J Med. 1986;314:605–613
  12. Houmard J, Tanner C, Slentz C, Duscha B, McCartney J, Kraus W. Effect of the volume and intensity of exercise training on insulin sensitivity. J Appl Physiol. 2004;96:101–106
  13. Brooks G, Fahey T, White T. Exercise Physiology: Human Bioenergetics and Its Applications. In: Mayfield: Mountain View; 1996;p. 749
  14. Ford E, Giles W, Dietz W. Prevalence of the metabolic syndrome among US adults: findings from the Third National Health and Nutrition Examination Survey. JAMA. 2002;287:356–359

 This work was supported by Grant HL-57354 from the National Institutes of Health, Bethesda, Maryland.

PII: S0002-9149(07)01673-6

doi: 10.1016/j.amjcard.2007.07.027

American Journal of Cardiology
Volume 100, Issue 12 , Pages 1759-1766 , 15 December 2007

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